doi: 10.1021/bi901180v
Last reviewed: May 31, 2026 Last updated: May 31, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
The resolving electron donor thiol can be glutathione, allowing the formation of a mixed disulfide, while the second donor thiol enables the reduction of the formed disulfide bonding
[DOI] [PubMed] [Google Scholar] 184.Baatrup E., Nielsen M.G., Danscher G
Quantification of GSH using LCMS Cells were incubated with 100 M of N -methyl maleimide (NMM) in PBS for 15 min at room temperature to derivatize all the small-molecule thiols
Prognosis is poor with only 10% of patients surviving longer than 90 days 1