Maryam Tabatabai Associate Vice President, Clinical Information Editorial team Maryam Tabatabai, PharmD Editor-In-Chief Associate Vice President, Clinical Information Carole Kerzic, RPh Executive Editor Drug Information Pharmacist Principal Nicole Kjesbo, PharmD, BCPS Executive Editor Clinical Program Development Director Senior Consultant panel Samantha Decker, PharmD Medical Pharmacy Clinical Pharmacist Natalee Felten, PharmD, BCPS Medical Pharmacy Clinical Pharmacist Andrea Henry, PharmD, MBA, BCPS Drug Information Pharmacist Principal Katie Lockhart Clinical Outcomes, Analytics, and Research Danny Melson Data Scientist Principal Olivia Pane, PharmD, CDCES Drug Information Pharmacist All brand names are property of their respective owners
Mechanism of action Prescription GLP-1 receptor agonists are synthetic peptides that directly bind to and activate GLP-1 receptors throughout your body
Risk Profile of Combination Use Stacking two incretin-based agents amplifies the most common adverse effects
GLP-1RAs can also enhance glycolytic and oxidative pathways via AMPK activation, thereby limiting ectopic lipid accumulation and lipotoxic stress [55, 56]
So often, patients invest time and money only to not be told how to keep weight off and eat the right weight to sustain
doi: 10.1177/2042018821997320 35 ZinmanBWannerCLachinJMFitchettDBluhmkiEHantelSet al
