2020;13(8):e237367
The major drawback of oral form of glutathione is its low bioavailability in humans.[] PARENTERAL PREPARATIONS To achieve the anticipated therapeutic levels and rapid onset of action, IV glutathione has been made available
The role of botanical triterpenoids and steroids in bile acid metabolism, transport, and signaling: Pharmacological and toxicological implications
Iron overload in the motor cortex induces neuronal ferroptosis following spinal cord injury
These work by binding and sequestering TNF-alpha, which is known to cause severe degradation of joints, cartilage, and entheses
Pharmacological inhibition of the MVA pathway impairs Sec-tRNA biogenesis, leading to GPX4 inactivation, diminished cellular antioxidant defenses, lipid peroxide accumulation, and ultimately ferroptosis induction ( Recent studies demonstrate that the bisphosphonate alendronate synergistically enhances paclitaxel efficacy, suppresses tumor metastasis, and modifies cytotoxic mechanisms in cancer therapy