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In December 2023, the European Medicines Agencys Pharmacovigilance Risk Assessment Committee announced an update on its review of GLP-1 RAs and suicidal thoughts and thoughts of self-harm, which began in July 2023

Relying solely on standard DRIs may be outdated, as some research finds higher therapeutic doses support better health outcomes

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(3) semaglutide in combination with BI8271 ( n =10)

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Damianaki A, Vagiakis E, Sigala I, et al