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Others warn against universal supplementation because of varying treatment responses, safety concerns over long-term use, and mixed outcomes in randomized controlled trials

Competitive structure remains moderately consolidated, with Nestl Purina PetCare, Mars Petcare, and Vetoquinol collectively holding significant market share, while regional manufacturers compete through specialized formulations, veterinary partnerships, and application-specific support near pet care distribution hubs

Yes, it is available for research purposes in the U.S., but it is not FDA-approved for general medical use

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Obviously, they occurred before the initiation of angiogenesis (Sikiric et al., 1993