"These drugs are thought to work by engaging part of the brain called the hypothalamus, which helps regulate a wide variety of hormones," says Jena Shaw Tronieri, Senior Research Investigator at Penn's Center for Weight and Eating Disorders and a co-author of the study
Proper hormone levels can help regulate energy expenditure, reduce cravings, and improve body composition
Call if food aversion keeps you from eating or drinking enough, is getting worse, comes with repeated vomiting, or leaves you feeling weak, dizzy, or clearly under-fueled
But it eliminates the combination for these individuals
These facilities use FDA-approved active pharmaceutical ingredients (semaglutide and tirzepatide) combined under strict quality and sterility standards equivalent to commercial manufacturing
Even modest weight loss of 5 to 10 percent can lead to meaningful improvements in blood sugar, blood pressure, metabolic liver disease, sleep apnea, joint pain, cardiovascular risk, and overall health