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Vitamin b12, or cobalamin, is a cofactor the body cannot manufacture

As of June 2026, the FDA's December 2024 Pharmacy Compounding Advisory Committee evaluation concluded that the criteria weighed against placing AOD-9604 (free base) or AOD-9604 acetate on the 503A Bulks List, and AOD-9604 is currently listed as Nominated but Withdrawn from FDA Category 2

Its not dramatic, but its directional

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Scientific findings depend on study design, methodology, participant characteristics, laboratory models, and many other variables

This is, to my knowledge, one of the first clinical trials to directly measure both muscle mass and muscle function together in incretin-treated patients