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doi: 10.9778/cmajo.20160058
Preventive Nutrition and Food Science, 26 (4), 367379
Keeping the medication in the refrigerator helps in several ways: Slows down chemical reactions that can break down the medication Protects the active ingredients from heat Helps maintain the medications potency and effectiveness Slows the growth of bacteria, mold, and other microorganisms Reduces the risk of contamination that could make the medication unsafe Proper storage is very important for compounded medications
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Along the way the two cover the range of peptides people actually ask about, how to separate credible science from marketing hype, and why "it didn't work for me" almost never means what people think it means
Endosomal versus plasma membrane signalling with a panel of GLP-1RAs was compared using targeted FRET cAMP biosensors (pmEpac2 and cytoEpac2), revealing that exendin-4 is biased in favour of cytoplasmic cAMP production compared to liraglutide (108)
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