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Tesamorelin arrived later and was engineered for a different purpose entirely: a durable, degradation-resistant GHRH analog aimed at the metabolic problem of visceral fat accumulation in people with HIV on antiretroviral therapy

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American Journal of Biomedical Science & Research , 15 (2), 153

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The impaired wound healing response observed in smokers can also hinder hepatic regeneration, thereby exacerbating fibrosis and increasing the likelihood of replication errors and de novo mutations, potentially linking to carcinogenesis [47, 48]