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The Gila monster enters the scene A solution to the difficulties with GLP-1 eventually came from a totally unexpected source - the Gila monster (figure 32)

(Left) In liver cells, GLP-1 can mediate cholesterol efflux by acting directly on LXR, or by inducing an increase in ATP-binding cassette transporter A1 (ABCA1) mRNA through Ca2+/calmodulin (CaM)-dependent protein kinase kinase/CAM-dependent protein kinase IV/Prolactin regulatory element binding (CaMKK/CaMKIV/PREB), increasing apolipoprotein AI (apo AI) mRNA and promoter expression, and increasing apo AI secretion, thereby mediating intracellular cholesterol efflux

New Trends Experim Clin Psychiatry

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Munger also addressed the genetic component that can make a child more prone to develop autism, stating, "There are a lot of genetic changes

(PubMed) Andres M, Sivera F, Falzon L, Buchbinder R, Carmona L