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The most well-known names are: Semaglutide the active ingredient in Ozempic (diabetes) and Wegovy (weight loss) Tirzepatide the active ingredient in Mounjaro (diabetes) and Zepbound (weight loss), which works on both GLP-1 and GIP receptors Clinical trials have shown average weight loss of 1522% of body weight with these medications when combined with lifestyle changes numbers that far exceed what most people can achieve through diet and exercise alone

p = 0.59) [37]

Clinical Implication Retatrutide may offer a more potent option for weight reduction, but long-term safety remains to be established

doi:10.1016/j.mam.2008.08.006 Franco R, Cidlowski JA

No independent testing of Zevay's program, medications, or providers was conducted

Exercise recommendations and guidance on physical activity