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In vitro investigations have demonstrated that cells infected with H pylori that have defective DNA repair systems experience increased oxidative stress and DNA damage ( In vivo studies using mice lacking a component of the base excision repair process revealed significant stomach lesions after H pylori infection ( H

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Metformin and the gut microbiome The gut microbiome and the metagenome (the microbial genome) are areas receiving increasing research attention, and are now considered as environmental factors that contribute to the development of many diseases, including obesity, the metabolic syndrome and type 2 diabetes [7884]

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