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Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts

Theres always a chance of a biochemical loss, but at this value its minimized

In humans, glutathione is produced by the liver and is essential for overall health

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Additionally, IGF-1 enhances expression and activity of enzymes involved in fatty acid metabolism, including carnitine palmitoyltransferase-1, the rate-limiting enzyme for fatty acid entry into mitochondria for oxidation

Arrows indicate IV injections