People with gut issues or genetic predispositions can have a harder time with severe nausea
Best for Maximum Weight Loss Injectable GLP-1s outperform oral GLP-1s in terms of weight loss in clinical trials, but results are mixed in real-world settings
Reduces inflammation and cholesterol GLP-1 medications decrease inflammationa key driver of heart disease
CrossRef Association of Metabolic Dysfunction-Associated Steatotic Liver Disease and Kidney Failure in the CKD Population Jin Kyung Kwon, Minsang Kim, Jinsun Lee, Jae-ik Oh, Jung Hun Koh, Min Woo Kang, Jeong Min Cho, Seong Geun Kim, Hyuk Huh, Sehyun Jung, Semin Cho, Soojin Lee, Eunjeong Kang, Yaerim Kim, Dong Ki Kim, Kyungdo Han, Sehoon Park Kidney International Reports .2026
Glucagon-like peptide-1 (GLP-1) receptor agonistsincluding semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)along with tirzepatide (Mounjaro, Zepbound), a dual GIP/GLP-1 receptor agonist, have transformed the management of type 2 diabetes and obesity
Side effects: How long to tough it out