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In one double-blind trial comparing GHK-Cu vs Matrixyl 3000, effects reduced wrinkles by 31.6% and improved skin firmness

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When hydroxocobalamin is given in high doses (such as during cyanide poisoning treatment), unique effects can be observed: patients often experience a transient reddening of the skin or mucous membranes and a reddish discoloration of the urine due to drug excretion