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8.7 Strategic implications for drug discovery Taken together, regulatory, commercial, and practical considerations suggest that underexplored peptidereceptor systems are best advanced through focused, indication-specific strategies that leverage their unique biological properties rather than forcing them into existing paradigms ( The final section synthesizes these insights into a decision framework for distinguishing peptide systems that merit renewed investment from those that should remain abandoned and articulates a forward-looking perspective on the future of peptide therapeutics

It is not a perfect product, but it is real medicine

The long-term safety profile is still being established

Wald test corrected for multiple testing using the Benjamini and Hochberg method

Vomiting is 17% versus 24%

These medicines, including semaglutide or tirzepatide, encourage the pancreas to produce insulin and slow down stomach emptying