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When applied topically or delivered via microneedling or injection, GHK-Cu influences gene expression related to skin remodeling, inflammation reduction, and antioxidant protection

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The rationale is straightforward: if BPC-157 signals the repair process and TB-500 enables cells to execute it, combining both may produce complementary effects

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The exact mechanism underlying these effects is not yet fully understood, though researchers suggest a significant role for ROS accumulation caused by AURA-A inhibition [79]