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Intracellularly, Liraglutide upregulated the expression of keratinocyte growth factor ( KGF ) in human chorionic membrane-derived mesenchymal stem cells, angiopoietin-1 ( ANG-1 ) in human bone marrow-derived mesenchymal stem cells, and surfactant protein C (SPC) in human amniotic membrane-derived mesenchymal stem cells, highlighting distinct trophic responses dependent on hMSC tissue origin [39]

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Despite the promising results, the glucose-responsiveness of these IPC remains limited

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Sustained, gradual loss is typical and healthier