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Glutathione S-transferases (GSTs) may also be involved in conjugating electrophiles generated from the reaction of hydroxyl radicals with lipids and DNA, and thus contribute to oxidative stress resistance (Marrs, 1996)

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Interestingly, the STAT3 transcription factor is the major inducer of the expression of this immunosuppressive armament, either directly or indirectly [9, 89, 93, 94]

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