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Risk Groups and Risk Factors Individuals with the diseases already described, primarily involving tumors of the liver, may develop hypercobalaminemia

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However, if the defenses are too weak, then infections cannot be handled or body cells can proliferate uncontrolled and grow to form tumors, which can become life threatening. In vivo, T-cell-specific ablation of murine Gclc prevented autoimmune disease but blocked antiviral defense, the Immunity article noted

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