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Prooxidant properties of naringenin may cause cytotoxicity to various cancer cell lines, apoptosis, and activation of one of the Mitogen-activated protein kinases, ASK1 resulting in apoptosis by ROS-mediated activation of ERK1/2 (Park et al

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K., Weghorst, C

Its reported interactions with circadian-associated pathways, including potential links to melatonin regulation, position DSIP as a model compound for investigating synchronization of biological rhythms and neuroendocrine coordination of sleep processes [3]