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By modulating macrophage polarization towards an M2 subtype, GLP-1RAs can inhibit inflammation occurring in the vessel lumen, an action which would alleviate the progression of atherosclerosis (Figure 2)

Semaglutide activates GLP-1 receptors in the brain, pancreas, and digestive system

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As individual needs vary, a doctor will determine the appropriate dose, frequency, and injection technique based on clinical judgment

A decrease in blood sugar causes semaglutide GLP-1 to increase insulin release, decrease glucagon release, and delay gastric emptying

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