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Though GLP-1 weight-loss users showed slightly larger spending reductions, the difference versus diabetes users was not statistically significant, the study found

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This may include a sensation of tightness in the abdomen, feeling satisfied with smaller portions of food, and a decreased appetite

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One clinical trial found that participants regained about two-thirds of their previously lost weight within one year of stopping subcutaneous semaglutide.[10] Maintaining a relationship with a healthcare provider may help support long-term success by offering guidance, monitoring progress, and helping you build sustainable habits