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Summary Cellular senescence, marked by irreversible cell cycle arrest and the secretion of proinflammatory factors, contributes to aging and cancer recurrence

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This case highlights that vitamin B12 deficiency can manifest primarily as deep sensory disturbance without typical upper motor neuron signs or radiological findings, particularly in older adults

MMA should drop once B12 is replete

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Front Immunol 9:978 Xin H et al (2009) Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells