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[PMC free article: PMC2682768] [PubMed: 19060907] 65

Early research focused on benefits for the gut, but because some animal studies suggested the compound could help promote blood vessel growth, calm inflammation and support tissue repair, researchers years later began testing it in cell and animal models of tendon, ligament, muscle, bone and cartilage injury

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To address copper-dependent toxicity in WD in human liver cells, we reanalysed the RNA sequencing data (GSE107323) [2], validated gene expression signatures and functionally addressed our findings in the HepG2 ATP7B knockout (ATP7B-KO) model [7]

Epithalon was originally derived from the pineal gland extract Epithalamin and retains the ability to stimulate and restore pineal gland function