Supplementary information is available at Cell Death Discoverys website Ethics This study did not involve human participants, human data, or human tissue, and did not require ethical approval
The next major step is the introduction of oral GLP-1 formulations, currently in clinical trials, which could make obesity treatment easier, safer, and more affordable
It is important to note that Phase 2 trials typically exclude participants with significant cardiovascular disease, which limits the generalisability of these safety findings to higher-risk populations
NanoBiT assay HEK 293T cells were seeded onto 6-well cell culture plates in DMEM containing 10% FBS and 1% sodium pyruvate at 37 C, 5% CO 2 before transfection
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