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Functional studies have identified many key genes that mediate breast cancer organ-specific metastasis, and the expression of these genes in the primary tumor is likely to forecast the patients organ-specific metastasis ( Bone is the most frequent site of breast cancer metastasis ( The second most common metastatic site of breast cancer is the brain ( Compared to other metastatic lesions, lung metastasis generally show phenotypes of aggressive growth and invasiveness (116)

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(2022) 145(3):e18e114