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Broadly speaking, inflammatory macrophages increase production of proinflammatory cytokines IL-6, TNF, IL-1, and type I interferons that create a harmful feedforward immune cell recruitment-activation cycle 2,74,104,105

Extensive progress in -omics technologies has unveiled the impact of various lifestyles and gut-microbiota/metabolites modulation in CKD patients compared to healthy controls and patients not exposed to these therapeutic measures

These showed that ashwagandha can modulate both innate and adaptive immune function in humans

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