Because the information provided was often limited and because these events can be influenced by other potential factors, the FDA determined that the information in these reports did not demonstrate a clear relationship with the use of GLP-1 RAs
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A positive readout would allow submission of an NDA to the FDA, with approval possibly following in 2027 and commercial availability shortly after
After that, the amount can be slowly raised to 1 mg every week
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Some side effects associated with TNF-alpha inhibitors are increased susceptibility to infections, like mycobacterium tuberculosis, bacterial, viral, or fungal