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Targeted modulation and site-specific administration of therapeutic drugs are made possible by the spatiotemporally programmable application of ultrasound, either with or without ultrasound contrast agents [278]

The DDX3X degrader J10 exhibits superior tumor-suppressive effects and enhances radiosensitivity compared to RK-33 Our next objective was to compare the anti-tumor efficacy of J10 with RK-33, a small molecule DDX3X inhibitor that has been shown to have anti-tumor effects [23]

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