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The compound consists of the amino acid sequence glycyl-L-histidyl-L-lysine coordinated with copper, forming a stable structure suitable for analytical investigation and method development

For example, in the cytosol of hepatocytes the steady-state ratio of NADP+/NADPH is approximately 0.1, which favors the use of NADPH in reductive biosynthetic reactions

Studies show that even a daily dose of 250 to 1,000 mg can increase glutathione levels [7]

Majewski 2003

Accessed June 11, 2026

We hope these assays and insights will be adopted more broadly to build larger datasets of GST substrate preferences, ultimately enabling more predictive frameworks for GST-mediated metabolism, similar to those established for CYP450s