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Exenatide exerts cognitive effects by modulating the BDNF-TrkB neurotrophic axis in adult mice

The limited secondary structure in these peptides reduces the hydrophobic hot spots that mediate benzyl alcohol destabilization in globular proteins

The new classes of obesity medicationsGLP-1 and GIP/GLP-1 receptor agonistshave approved uses for diabetic patients, but theyre being prescribed for obesity both on- and off-label, depending on the drug in question

These are reports from doctors or patients after the drug was already approved

Extended-release formulations reduce these issues substantially

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