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The three main long-acting insulins, Tresiba (Degludec insulin), Xultophy (Degludec insulin/liraglutide), and Levemir (Detemir insulin) had sales of 9.91 billion Danish Krone, 4.67 billion Danish Krone, and 4.5 billion Danish Krone, respectively

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Citation54 These species-specific patterns reflect underlying physiological characteristics, including the cell envelope, efflux systems, and thiol metabolism

Notably, GGCT overexpression paradoxically enhanced the metabolic flux from Gln to GSH m + 5 (Fig