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10.1021/jf9025458 18 FleschhutJ.KratzerF.RechkemmerG.KullingS

However, theres a growing trend thats capturing attention both in clinical practice and popular culture: GLP-1 microdosing

If you experience shortness of breath, chest pain, fainting, fluid retention in the legs or feet, or difficulty exercising, tell your healthcare provider right away

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The phase III REDEFINE 1 study results, released in December 2024, showed that the CagriSema treatment group lost 22.7% of their weight after 68 weeks, significantly outperforming the single-target control drugs (semaglutide group lost 16.1%, cagrilintide group lost 11.8%)