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Modern GLP-1 receptor agonists were developed to overcome this limitation and produce sustained therapeutic activity

Topiramate is a carbonic anhydrase inhibitor, which means it can change the acidity of your blood and urine

By creating microscopic channels, they can bypass the outer barrier and deposit drugs directly into the dermis

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*Correspondence: Marc Diederich, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, South Korea e-mail: [email protected] Michael Schnekenburger, Tommy Karius, and Marc Diederich have contributed equally to this work