In a study of two psoriasis patients with diabetes, liraglutide therapy for 6 weeks resulted in rapid clinical improvement, characterized by increased circulating i NKT cells and they also demonstrated in vitro that GLP-1 induced a dose-dependent reduction of cytokine secretion from i NKT cells [77]
If you find that any side effects persist for longer than this or get worse over time, stop taking your medication and contact your prescriber as soon as possible
Vinik, A
As GLP-1 RAs become more prevalent in treating diabetes and patients with cardiovascular disease (CVD) or risk factors for CVD, clinicians will ultimately manage the practical aspects of patient selection, dosing, special considerations, and side effects of these medications
Other frequent side effects include: Headache and dizziness Fatigue and decreased energy Injection site reactions Dyspepsia and gastro-oesophageal reflux More serious but less common adverse effects include pancreatitis, gallbladder disease, and hypoglycaemia (particularly in patients taking concomitant diabetes medications)
The only notable positive outcome was the reduction of A42 in plasma neuronal EVs, which may reflect the neuronal condition in the systemic circulation
