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Many people report that food no longer drives their thoughts or behavior in the same way. In 2012, Skibickas lab was the first to demonstrate reduced alcohol reward and motivation in animal models treated with a GLP-1 analog

Nutrition 109 , 111992 (2023)

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5 Similarly, Vilsbll found in a post hoc mediation analysis of SUSTAIN 6 that the large and rapid reduction of HbA 1c percentage in patients on semaglutide seemed to drive the DR complications observed in that group

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