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We found that ethanol administration caused a 2.3-fold increase in the 3-NT protein level, which paralleled a significant induction of 3-NT protein staining that was, again, distinctly colocalized with the neuronal marker NeuN, suggesting that 3-nitrotyrosine protein adducts were formed because of iNOS induction (Figs

Therapeutic targeting of ER stress and ERAD in NDDs ERAD enhancers Enhancing ER-associated degradation (ERAD) represents one therapeutic avenue

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1 A subsequent matched study comparing uveal melanoma metastatic risk found that eyes with ODM were overall twice as likely to have systemic metastasis compared to eyes without ODM