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KEAP1 acts as an OS sensor to regulate NRF2 turnover within the cell/body, while NRF2 activation leads to the production of antioxidant and detoxifying substances that decrease OS [66,67,68]

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After incubation, ROs were washed three times with PBS, and fluorescence intensity was measured by 3D-ARQ using the following parameters: Mode: Fluorescent top reading

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1 L-ornithine l-aspartate was successfully used to prevent brain edema in rats, but in humans, no benefit was seen compared with placebo