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Both drugs target the GLP-1 receptor and combining them could increase the risk of gastrointestinal side effects such as nausea, vomiting, and diarrhea, while also posing risks of hypoglycemia

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Tip: If you feel hungry, eat

For triathletes training 10 to 20 hours per week, these drugs can compromise carbohydrate absorption during racing, blunt thirst cues and increase the likelihood of RED-S if nutrition is not carefully managed

If you are also using insulin, do not inject tirzepatide and insulin into the same spot at the same time, though the same general body region is fine as long as the exact sites differ