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Recently, it has been demonstrated that replacing hydroquinone with a potent cosmetic depigmenting agent, isobutylamido-thiazolyl-resorcinol, in the trio provides at least similar efficacy and better tolerance [206]

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Microinjection of histone deacetylase inhibitor into the ventrolateral orbital cortex potentiates morphine induced behavioral sensitization

Safety data indicate mostly mild injection-site reactions

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You must use a backup (non-oral) method for 4 weeks after starting and 4 weeks after each dose increase