doi: Blundell, J., Finlayson, G., Axelsen, M., et al
I was borderline pre-diabetic, and my doctor said if I didnt make changes, I would most likely become diabetic in the next few years, he said
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The study results, published in the July 15, 2026, online edition of The Lancet Gastroenterology & Hepatology , address a major unmet need for people with metabolic dysfunctionassociated steatohepatitis (MASH), a serious form of fatty liver disease that can lead to cirrhosis, liver failure, and the need for transplantation
Weight loss at this dose continues at three to six pounds monthly for most people
The strongest effects accumulate at higher dose levels (10-15mg) as tirzepatide reaches its full GIP-plus-GLP-1 potency