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Additionally, Pistacia lentiscus supplementation ameliorated decreases in plasma-free amino acids observed in patients with UC receiving placebo, indicating a potential role in improving metabolic profiles in UC [167]

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C4 (7- -hydroxy-4-cholesten-3-one) is positively associated with FGF19 and total BAs in IBS-D individuals, which indicates that the loss of BAs in feces leads to an increase in BA production