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This is not a complete list of side effects and others may occur
Gribble, F
Competing interests The authors declare no competing interests
Substituting tirzepatide for semaglutide is a theoretical extension of that idea pairing an amylin analog with a more potent dual incretin agonist but it is important to repeat that this specific pairing has not been validated in a dedicated human combination trial
Human clinical trials are limited, and more data is needed to fully understand safety, efficacy, and optimal protocols
In theory, this could support tissue repair, but it might also create risks if misregulated particularly in women with clotting disorders or cardiovascular history
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