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We acknowledge several shortcomings to our study, including that the effects of exendin-9-39 cannot exclude the potential for signaling of glucagon through the GLP-1R (8386), in addition to active GLP-1 (87)

These pseudo-observations serve to anchor the doseresponse relationship at a physiologically plausible baseline (i.e., no treatment effect in the absence of exposure), thereby preventing unrealistic extrapolation near zero dose

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Another controlled clinical trial was conducted on 62 hypercholesterolemic men and women 1865 years of age by feeding 80 g/day oatmeal revealed a consistent relationship between micro-organism modification, the significant amelioration of hypercholesterolemia by lowering TC, LDL-C, and apolipoprotein B [58]

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A 122 , 125132 (2003)