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Stroke and cognitive impairment: understanding the connection and managing symptoms

541 M3258 treatment results in strong antitumor activity in multiple myeloma xenograft models and shows enhanced effectiveness relative to ixazomib or bortezomib

Furthermore, GSEA of all DEGs confirmed enrichment of pathways involving these 16 genes, including adaptive immune system terms, with directionality consistent with the primary pre/post-treatment comparison (Supplementary Fig

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Indeed, compared to cytosolic G6PD5.1-GFP, G6PD5.4-GFP and G6PD5.5-GFP localized to distinct cellular sites (Figure 2C), with only the N-terminal domain of G6PD5.4 fused to GFP still showing local accumulations