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There is evidence that higher Lp(a) levels are strongly associated with decreased estimated glomerular filtration rate, a phenomenon observed in both patients with mild renal impairment and those on hemodialysis for end-stage renal disease [187,188,189,190]

[6] Patients with a history of severe allergic reactions to similar injectable vitamins should not receive this product, or should undergo desensitization under close medical supervision if the therapy is deemed essential