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The Cu2+ ion is coordinated by the histidine imidazole nitrogen and the N-terminal amino group of glycine, forming a specific metal-peptide complex

Each peptide was selected for its distinct mechanism of action, creating a synergistic therapeutic approach that addresses tissue regeneration, inflammation control, immune modulation, and cellular rejuvenation simultaneously

Front Cell Neurosci 10:

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This novel link to epigenetic plasticity during epithelial-to-mesenchymal transition adds to previous studies showing a role for iron in metastatic ability likely through downregulation of N-myc downstream-regulated gene 1 (NDRG1) [16], a metastatic suppressor that is usually decreased in several types of cancer

Bile acids are mainly composed of free and conjugated bile acids (Figure 1), free bile acids: cholic acid (CA), deoxycholic acid (DCA), chenodeoxycholic acid (CDCA) and lithocholic acid (LCA)