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Tier 3 (same-day evaluation): Right-upper-quadrant pain radiating to the shoulder, severe abdominal pain, jaundice, signs of dehydration (orthostatic dizziness, dark urine, heart rate above 100 at rest), or inability to tolerate any oral fluids for 12 hours

No perceived negative side effects

In absence of further evidence, lipoic acid supplementation during pregnancy should only be considered under strict medical supervision

Synapsin is exclusively expressed in neurons, and confirmation of Gipr KO revealed that Gipr expression was lower in the brainstem, hypothalamus and hippocampus of Gipr Syn/ mice than in Gipr fl/fl control mice, while Gipr expression in pancreatic islets was similar between the two genotypes (Fig

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