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However, because Nrf2 activation primarily affects the lens epithelium and cortex, alternative strategies are required to replenish glutathione in the lens nucleus

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However, the role of iron in neuropsychiatric conditions remains less studied, as most clinical evidence suggests that iron deficiency rather than iron overload is associated with mood disorders (Duarte-Silva et al., 2025)

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PMID: 63 JanikiewiczJ.SzymanskiJ.MalinskaD.Patalas-KrawczykP.MichalskaB.DuszynskiJ.et al